BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Events//NONSGML v1.0//EN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTART;TZID="Pacific Time (US & Canada)":20261102T161000
DTEND;TZID="Pacific Time (US & Canada)":20261102T170000
SUMMARY:CHE 598 Seminar: Developmentally Inspired Approaches For Tendon and Muscle Tissue Engineering
LOCATION:Schweitzer Engineering Hall (SEH) Building, 150 SE Spokane Street, Pullman, WA 99164
DESCRIPTION:SPEAKER: Dr. Nathan Schiele, Associate Professor, Department of Chemical & Biological Engineering, University of Idaho\n\nBIOGRAPHY:\n\nDr. Nathan Schiele is an Associate Professor in the Department of Chemical & Biological Engineering at the University of Idaho (UI). He graduated with a B.S. in Mechanical Engineering from the University of Dayton. He received his Ph.D. in Biomedical Engineering from Rensselaer Polytechnic Institute, where he focused on cell printing and tendon tissue engineering. As a postdoctoral fellow at Tufts University, Dr. Schiele was supported by an NIH-sponsored fellowship through the Institutional Research and Academic Career Development Award (IRACDA) program, where he explored mechanical and biochemical factors that regulate tendon formation. Dr. Schiele has been faculty at UI since 2015 and teaches upper-level courses in tissue biomechanics and tissue engineering as well as courses for first-year engineering students. Dr. Schiele is also the UI Campus Leader and Student Coordinator for the NIH-funded Idaho IDeA Network of Biomedical Research Excellence (INBRE) program, which supports undergraduate student research across Idaho. His musculoskeletal tissue engineering research at UI has been funded by the NIH, USDA, and NSF.\n\n \n\nABSTRACT:\n\nTendon injuries are difficult to treat and typically have poor return to function. As tendons transfer mechanical forces from muscle to bone for normal movement, reduced function negatively impacts quality of life. A major challenge for addressing tendon injuries with new tissue engineering and regenerative approaches is a limited understanding of how tendons develop their mechanical function. Our lab has been focused on addressing this gap in knowledge by taking a developmentally inspired approach. We have been exploring the mechanical, biochemical and cellular factors that are involved in normal tendon formation and applying those factors in our tissue engineering strategies. We have identified developmentally inspired factors that impact tenogenic differentiation of stem cells and the production of enzymes that regulate collagen crosslinking. Recently, we have been exploring regulators of tendon formation using a scaffold-free, cell self-assembled in vitro three dimensional (3D) non-animal model/novel alternative methodology (NAM) that mimics the highly cellular stages of embryonic tendon formation. We are also extending this approach to study muscle-tendon interactions, and we are employing tissue engineering principles to advance muscle formation.\n\n 
BEGIN:VALARM
ACTION:DISPLAY
DESCRIPTION:REMINDER
TRIGGER;RELATED=START:-PT00H15M00S
END:VALARM
END:VEVENT
END:VCALENDAR