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DTSTART;TZID="Pacific Time (US & Canada)":20201030T141000
DTEND;TZID="Pacific Time (US & Canada)":20201030T160000
SUMMARY:Oral Prelim Examination &#8211; Jessica Carder
LOCATION:Online
DESCRIPTION:Jessica Carder (Brozik Group)\n\nZOOM ONLY\n\nTitle: Stochastic Biophysics of More Natively Folded Recombinant Human Aquaporin-4 Orthogonal Array of Particles: A Protein Tracking Study\n\nAbstract: Aquaporin-4 (AQP4) is the central nervous system (CNS) water channel protein in charge of controlling water homeostasis and neuronal activity. AQP4 exists in two main isoforms in the CNS, M1 and M23, with M23 being the isoform that favors stabilization by aggregation into orthogonal arrays of particles (OAPs). What role these OAPs play in the membrane of cells is still largely unknown and the dynamics of OAP assembly in the plasma membrane remain elusive. Through a collaboration with the Nicchia group from the University of Bari, techniques have been developed using insect cell lines to isolate and express the M23-AQP4 isoform in its authentically folded state in an in vitro environment. The goal of this research is to take natively folded AQP4 aggregates, and using both in vitro and in vivo t-+echniques, discover how different environmental cues effect OAP assembly kinetics and equilibrium states.\n\nZoom info:\n\nJoin from PC, Mac, Linux, iOS, or Android: https://wsu.zoom.us/j/96579724027?pwd=aVlSWHBzYjNTTnhPYm01ank2MDQ5UT09\n\nMeeting ID: 965 7972 4027\n\nPasscode: 425653\n\nPlease refer to this guide on Joining WSU Zoom Meetings before trying to join the meeting.\n\nhttps://confluence.esg.wsu.edu/display/KB/Zoom+-+Joining+Meetings+and+Best+Practices\n\nNote: Zoom Account authentication is required to join this meeting.\n\nJoin from WSU Conference Room System (Polycom)\n\n1. Using the touch panel, or remote control,  select &#039;Place a Call&#039;\n\n2. Enter the IP Address including periods: 162.255.37.11\n\n3. Press the pound key twice &#039;##&#039;\n\n4. Enter the Meeting ID: 965 7972 4027\n\n5. Press &#039;Call&#039;\n\n6. Enter Passcode: 425653\n\nJoin from Conference Room System with SIP\n\n96579724027@zoomcrc.com\n\nShare Screen/Content Wirelessly\n\nGo to https://share.zoom.us and enter Meeting ID: 965 7972 4027\n\nPhone Call (long distance)\n\n+1 253 215 8782\n\n+12532158782,,96579724027# US (One Tap Mobile Call)\n\nFind your international phone number: https://wsu.zoom.us/u/abGFp9EW0\n\nFor technical support with WSU conference rooms, contact your local IT team\n\nFor support or feature requests, please go to https://its.wsu.edu/wsu-video-conferencing-services/\n\n
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