AER Chemistry Seminar — Elizabeth Groetsema, Chemistry PhD Student

About the event

Title: Recent Advances for MS/MS in Miniature Linear Ion Trap Mass Spectrometers

Abstract: Mass spectrometers have historically been revered for their accuracy and precision. Further techniques, such as MS/MS where mass analysis is performed more than once on an analyte, have been able to add an additional level of specificity to identification of a wide variety of analytes. However, the large size and high cost of mass spectrometers creates obstacles for accessibility and widespread application of these instruments. The miniaturization of mass spectrometers seeks to solve these problems without sacrificing the capabilities that mass spectrometry is known for. Linear ion trap mass analyzers have proven to be an optimal choice for miniaturization due to their more simplistic geometry and high ion trapping capacity. This presentation will review recent developments for several MS/MS scanning types (product ion scans, multi-reaction monitoring scans, precursor ion scans, and neutral loss scans) in miniature linear ion traps which provide a multitude of new capabilities for these small instruments. Successful miniaturization will allow for mass spectrometry to be used for on-site analysis in many different fields, such as forensics, food and agriculture, and medicine.