About the event
Speaker: Dr. Qian Wang, Dept. of Chemistry and Biochemistry, Univ. of South Carolina
Title: Virus Engineering – a crosstalk of bioconjugation chemistry and biomaterials science
Abstract: Over the past two decades, viruses have been employed as natural nanoscale materials in a variety of applications due to their distinct features, including a narrow size distribution, versatile functionality, unique surface morphology, and biocompatibility. In addition to direct bioconjugation, reengineering their structures with specific functional groups, either genetically or post-translationally, is often required before accomplishing their final uses. In this talk, I will discuss our efforts in developing novel bioconjugation strategies, including hijacking the biosynthetic pathway and applying electrochemistry-based organic synthesis, to engineer different virus particles for cancer immunotherapy applications.