Voiland School of Chemical Engineering and Bioengineering Graduate Seminar Series

About the event

The Gene and Linda Voiland School of Chemical Engineering and Bioengineering is hosting a seminar presented by Shuang Guo, Ph.D. Candidate, Voiland School of Chemical Engineering and Bioengineering, Washington State University.

Shuang Guo earned his Bachelor’s Degree in Food Science and Master’s Degree in Analytical Chemistry from his home country, China. During his Master Degree, he worked on detection and quantitation of cancer biomarkers, especially in glycosaminoglycan (GAG) related biomarkers, and he found elevation of specific chondroitin sulfate disaccharides may indicate liver related disease progression and cancer.

He began the Engineering Science (Bioengineering) doctorate program at Washington State University in the fall semester, 2014. His research focus is studying miniaturized biomarker detection and quantitation methods.

Application of Paper-based Isotachophoresis technology for Rapid Biomarkers Detection

Capable of early diagnosis of certain diseases in point-of-care testing (POCT) is of paramount importance because early detection can lead both improved prognosis and survival rates. His research aims to overcome the technical barrier by developing a disposable paper-based isotachophoresis (ITP) technology for rapid analytes isolation and analysis. Running with a discontinuous electrolyte system, ITP can potentially concentrate samples by orders of magnitude in minutes with minimal sample consumption. To develop the technique, paper membrane was used for fabricating paper channels, followed by assembling the channels on a 3D printed cartridge device. The paper-based ITP device is capable of concentrating of analytes ranges from 100 to 700 fold in less than 10 minutes, demonstrating that paper-based ITP is a viable POCT for detecting multiple analytes and diseases that demand higher sensitivity.